•教育背景、工作经历
2020-至今 兰州大学化学化工学院,功能有机分子化学国家重点实验室,副教授
2015-2020 兰州大学化学化工学院,功能有机分子化学国家重点实验室,讲师
2010-2015 兰州大学化学化工学院(导师:房建国 教授),理学博士,
2006-2010 兰州大学化学化工学院,理学学士
•研究兴趣
化学生物学及药物化学
•代表成果
1. Assay of Selenol Species in Biological Samples by the Fluorescent Probe Sel-Green. Baoxin Zhang and Jianguo Fang*, Method. Enzymol. 2022, 662, 259.
2. A Novel off-on Fluorescent Probe for Specific Detection and Imaging of Cysteine in Live Cells and in vivo. Baoxin Zhang, Haijuan Zhang*, Miao Zhong, Song Wanga, Qianhe Xua, Dong-Hyung Cho, and Hongdeng Qiu*. Chinese Chem. Lett. 2020, 31, 133-135.
3.Thioredoxin reductase inhibitors: a patent review. Baoxin Zhang, Junmin Zhang, Shoujiao Peng, Ruijuan Liu, Xinming Li, Yanan Hou, Xiao Han and Jianguo Fang*. Expert. Opin. Ther. Pat. 2017, 27, 547-556.
4. Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications. Baoxin Zhang, Chunpo Ge, Juan Yao, Yaping Liu, Huichen Xie, and Jianguo Fang*. J. Am. Chem. Soc. 2015, 137, 757-769.
5. Synthesis of xanthohumol analogues and discovery of potent thioredoxin reductase inhibitor as potential anticancer agent. Baoxin Zhang, Dongzhu Duan, Chunpo Ge, Juan Yao, Yaping Liu, Xinming Li, and Jianguo Fang*. J. Med. Chem. 2015, 58, 1795-805.
6. Synthesis of piperlongumine analogues and discovery of nuclear factor erythroid 2-related factor 2 (Nrf2) activators as potential neuroprotective agents. Shoujiao Peng, Baoxin Zhang, Xianke Meng, Juan Yao, and Jianguo Fang. J. Med. Chem. 2015, 58, 5242-5255.
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