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谢新刚

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谢新刚

博士、副教授

电话:+86-13919353465

邮箱:xiexg@lzu.edu.cn

•教育背景、工作经历

2012-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室,副教授

2010-2012           兰州大学化学化工学院、功能有机分子化学国家重点实验室,讲师

2006-2010           香港中文大学 (导师: 黄乃正),博士后

2001-2006           兰州大学,理学博士

1997-2001           兰州大学,理学学士

•荣誉奖励

2015               甘肃省自然科学一等奖(排名第二)

2007               甘肃省自然科学二等奖(排名第三)

2007               Tetrahedron Letters Most cited paper 2004-2007 Award

•研究兴趣

主要从事绿色、高效的合成方法学及具有良好生理活性的天然产物全合成研究

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•代表成果 

1. Total syntheses of (−)-15-oxopuupehenol and (+)-puupehenone and formal syntheses of (−)-puupehenol and (+)-puupehedione, Huayue Song, Lin Liu, Mingyang Yang, Guangmiao Wu, Peng Chen, Xingang Xie * and Xuegong She, Org. Chem. Front., 20201, 35−42.

2. Synthetic studies towards daphniyunnine B: Construction of AC bicyclic skeleton with two vicinal all carbon quaternary stereocenters, Haiyu Sun, Guangmiao Wu and Xingang Xie*, Chinese Chem. Lett., 2019, 30, 1538−1540.

3. Concise formal synthesis of (+)-pyripyropene A, Tao Li, Guangmiao Wu, Shangbiao Feng, Xiaojun Hu, Weiwei Zhang, Shouchu Tang, Xingang Xie*, Xuegong She, Tetrahedron, 201975, 3939−3942.

4. Total synthesis of (-)-8-epi-chromazonarol enabled by a unique N2H4•H2O promoted intramolecular oxa-Michael cyclization reaction, Lin Liu, Hua-Yue Song, Peng Chen, Zi-Yun Yuan, Shang-Biao Feng, Wei-Wei Zhang, Bo-Wen Fang, Xin-Gang Xie*, Xue-Gong She, Org. Chem. Front. 2018, 5, 3013-3017.

5. Visible-light promoted dithioacetalization of aldehydes with thiols under aerobic and photocatalyst-free conditions, Zhi-Min Xing, Ming-Yang Yang, Hai-Yu Sun, Ze-Min Wang, Peng Chen, Lin Liu, Xiao-Lei Wang, Wang*,  Xin-Gang Xie*, Xue-Gong She, Green Chem. 2018, 20, 5117-5122.

6. A rapid construction of the ABC tricyclic skeleton of malabanone A, Tao Li,  Guang-Miao Wu, Shang-Biao Feng, Ze-Min Wang, Xin-Gang Xie*, Xue-Gong She,  Org. Biomol. Chem. 2018, 16, 8491-8494.

7. “Rapid construction of complex tetracyclic frameworks via a gold(I)-catalyzed tandem 1,2-acyloxy migration/[3 + 2] cycloaddition/Friedel–Crafts type cyclization reaction of linear enynyl esters”. Sun, H.-Y..; Xu, S.-Y.; Xing, Z.-M.; Liu, L.; Feng, S.-B.; Fang, B.-W.; Xie, X.-G.*; She, X.-G. Org. Chem. Front. 2017, 4, 2109–2113.

8. “Rapid construction of the 6/6/5 tricyclic framework via a tandem radical cyclization reaction and its application to the synthesis of 5-epi-7-deoxy-isoabietenin A”. Zhang, H.; Ma, S.-Q.; Xing, Z.-M.; Liu, L.; Fang, B.-W.; Xie, X.-G.*; She, X.-G.* Org. Chem. Front. 2017, 4, 2211–2215.

9. “Visible-Light-Promoted Dual C−C Bond Formations of Alkynoates via a Domino Radical     Addition/ Cyclization Reaction: A Synthesis of Coumarins”. Feng, S.-B.; Xie, X.-G.*; Zhang, W.-W.; Liu, L.; Zhong, Z.-L.; Xu, D.-Y.; She, X.-G. Org. Lett. 2016, 18, 3846−3849.

10. “An Efficient Synthesis of Benzazocines by Gold(I)-Catalyzed Tandem 1,2-Acyloxy Shift/[3+2] Cycloaddition of Terminal 1,9-Enynyl Esters”. Feng, S.-B.; Wang, Z.-S.; Zhang, W.-W.; Xie, X.-G.*; She, X.-G. Chem. Asian J. 2016, 11, 2167–2172.

11. “Concise Total Synthesis of Isospongian Diterpenoid (±)-Polyrhaphin D”. Wang, Z.-M.; Xing, Z.-M.; Liu, L.; Zhang, H.; Zhang, Z.-L.; Xie, X.-G.*; She, X.-G. ChemistrySelect 2016, 1, 2225–2227.

12. “Gold(I)-Catalyzed Tandem Reaction of γ-Amino-Substituted Propargylic Esters to Pyrrolines and its Application in the Formal Synthesis of (±)-Aphanorphine”. Wang, Z.-S.; Zheng, H.-J.; Yang, J.; Xie, X.-G.*; She, X.-G.* Adv. Synth. Catal. 2015, 357, 2082–2088.

13. “Scalable, efficient total synthesis of (+)-mupirocin H”. Zhao, C.-G.; Yuan, Z.-Y.; Zhang, Y.-Y.; Ma B.; Li H.-L.; Tang, S.-C.; Xie, X.-G.*; She X.-G.* Org. Chem. Front. 2014, 1, 105-108.

14. “Enatioselective total synthesis of (-)-Walsucochin B”. Xu, S.-Y.; Gu, J.-X.; Li, H.-L.; Ma, D.-H.; Xie, X.-G.*, She, X.-G.*, Org. Lett. 2014, 16, 1996-1999.

15. “Concise Formal Syntheses of the Amaryllidaceae Alkaloids (±)-Tazettine and (±)-6a-Epi- pretazettine: Construction of the Core Skeleton via Tandem Intramolecular Oxidative Friedel– Crafts / Aza-Michael Reaction”. Ma, D.-H.; Zhao, C.-G.; Li, H.-L.; Qi, J.; Zhang, L.; Xu, S.-Y.; Xie, X.-G.*; She, X.-G.* Chem. Asian. J. 2013, 8, 364-368.

16. “Concise Enantioselective Synthesis of Cephalosporolide B, (4R)-4-OMe-Cephalo- sporolide C, and (4S)-4-OMe-Cephalosporolide C”. Ma, B.; Zhong, Z.-L.; Hu, H.-T.; Li, H.-L.; Zhao, C.-G.; Xie, X.-G.*; She, X.-G.*Chem. Asian. J. 2013, 8, 1391-1394.

17. “Tandem Oxidative Dearomatization/Intramolecular Diels-Alder Reaction for Construction of the Tricyclic Core of Palhinine A”. Zhao, C.-G.; Zheng, H.-J.; Jing, P.; Fang, B.-W.; Xie, X.-G.*; She, X.-G.* Org. Lett. 2012, 14, 2293-2295.

18. “Total Synthesis of (±)-Kopsihainanine A”. Jing, P.; Yang, Z.; Zhao, C.-G.; Zheng, H.-J.; Fang, B.-W.; Xie, X.-G.*; She, X.-G.* Chem. Eur. J. 2012, 18, 6729-6732.

19. “Rapid Construction of the [6-6-6-5] Tetracyclic Skeleton of the Daphniphyllum Alkaloid Daphenylline”. Li, H.-L.; Zheng, J.-Y.; Xu, S.-Y.; Ma, D.-H.; Zhao, C.-G.; Fang, B.-W.; Xie, X.-G.*; She, X.-G.* Chem. Asian. J. 2012, 7, 2519-2522.

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