赵高原

博士、教授、博士生导师

电话：

+86-13993199757

邮箱：

zhaogy@lzu.edu.cn

•教育背景、工作经历

2024-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室，教授

2023-2024           普渡大学，研究员

2019-2023           纽约州立大学石溪分校，博士后

2016-2019           纽约州立大学奥尔巴尼分校，博士后

2011-2016           兰州大学，理学博士

2007-2011           兰州大学，理学学士

•研究兴趣

糖类精准修饰方法学，糖类天然产物全合成，糖疫苗研发

•代表成果

1. Visible-Light-Induced Phosphine-Catalyzed 1,3-Bromodifluoroalkylation of Allyl Esters via 1,2-Radical Migration. Zhao G, Lim S, Musaev D G*, Ngai M-Y*, J. Am. Chem. Soc. 2023, 145, 8275-8284.

2. Excited-State Palladium-Catalyzed α-Selective C1-Ketonylation. Zhao G, Mukherjee U, Zhou L, Mauro J N, Wu Y, Liu P*, Ngai M-Y*, CCS Chemistry 2023, 5, 106-116.

3. C2-Ketonylation of Carbohydrates via Excited-State Palladium-Catalyzed 1,2-Spin-Center Shift. Zhao G, Mukherjee U, Zhou L, Wu Y, Yao W, Mauro J N, Liu P*, Ngai M-Y*, Chem. Sci. 2022, 13, 6276-6282.

4. Excited-State Palladium-Catalyzed Radical Migratory Mizoroki-Heck Reaction Enables C2-Alkenylation of Carbohydrates. Yao W^#, Zhao G^#, Wu Y, Zhou L, Mukherjee U, Liu P*, Ngai M-Y*, J. Am. Chem. Soc. 2022, 144, 3353-3359.

5. Nickel-Catalyzed Radical Migratory Coupling Enables C-2 Arylation of Carbohydrates. Zhao G, Yao W, Kevlishvili I, Mauro J N, Liu P*, Ngai M-Y*, J. Am. Chem. Soc. 2021, 143, 8590-8596.

6. Excited-State Palladium-Catalyzed 1, 2-Spin-Center Shift Enables Selective C-2 Reduction, Deuteration, and Iodination of Carbohydrates. Zhao G^#, Yao W^#, Mauro J N, Ngai M-Y*, J. Am. Chem. Soc. 2021, 143, 1728-1734.

7. Visible-Light-Induced Photoacid Catalysis: Application in Glycosylation with: O -Glycosyl Trichloroacetimidates. Zhao G, Li J, Wang T*, Chem. Commun. 2021, 57, 12659-12662.

8. Stereoselective Synthesis of 2-Deoxyglycosides from Glycals by Visible-Light-Induced Photoacid Catalysis. Zhao G, Wang T*, Angew. Chem. Int. Ed. 2018, 57, 6120-6124.

9. Visible-Light-Mediated Thiol-Ene Reactions through Organic Photoredox Catalysis. Zhao G, Kaur S, Wang T*, Org. Lett. 2017, 19, 3291-3294.

10. Bioinspired Collective Syntheses of Iboga-Type Indole Alkaloids. Zhao G, Xie X, Sun S, Yuan Y, Zhong Z, Tang S, She X*, Org. Lett. 2016, 18, 2447-2450.

11. Domino Intramolecular Diels-Alder Reactions to Construct a 6/6/5/5 Fused Tetracyclic Framework. Zhao G, He M, Li H, Duan S, Yuan Z, Xie X, She X*, Chem. Commun. 2015, 51, 17321-17323.