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厍学功

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厍学功

博士、教授

电话:+86-931-8912276

邮箱: shexg@lzu.edu.cn

•教育背景、工作经历

2002-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授

2001-2002           美国俄勒冈大学,博士后

1999-2001           美国科罗拉多州立大学,博士后

1996-1999           兰州大学,理学博士

1993-1996           西北大学,理学硕士

•荣誉奖励

2017                    国华杰出学者奖领军人才奖

2016                    ACP Lectureship Award

2015                   甘肃省自然科学一等奖

2012                   甘肃省优秀专家

2011                   国家杰出青年基金

2010                   药明康德生命化学研究奖

•研究兴趣

1. 具有良好生物活性复杂天然产物的不对称全合成研究

2. 高效、环境友好的有机合成方法学研究

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•代表成果

1. A copper-catalyzed radical coupling/fragmentation reaction: efficient access to β-oxophosphine oxides,Shangbiao Feng, Jinlai Li, Feifei He, Tao Li, Huilin Li, Xiaolei Wang, Xingang Xie and Xuegong She*, Org. Chem. Front., 2019, 6, 946-951.

2. A concise approach to the tricyclic framework of longipinane- and ent-longipinane-type sesquiterpenoids, Min He, Jiuzhou Yi, Gaoyuan Zhao, Peiqi Chen, Dan Long, Xiaojun Hu, Huilin Li,Xingang Xie, Xiaolei Wang and Xuegong She*, Org. Chem. Front., 2019, 6, 383-387.

3. Total Synthesis of Aspidofractinine Alkaloid Paucidirinine, Weiwei Zhang, Shanhao Lin, Chenglong Du, Shangbiao Feng, Zaimin Liu, Jing Zhang, Xingang Xie, Xiaolei Wang, Huilin Li, and Xuegong She*, J. Org. Chem. 2019, 84, 1111−1116.

4. Asymmetric Total Synthesis of (+)-Winchinine B, Zaimin Liu, Xiaolin Ju, Shiqiang Ma, Chenglong Du, Weiwei Zhang, Huilin Li, Xiaolei Wang,Xingang Xie, and Xuegong She*, J. Org. Chem., 2019, 84, 14994−15000.

5. Construction of the Tetracyclic Core of Calyciphylline B‑Type Daphniphyllum Alkaloids, Chenglong Du, Jing Fang, Jinyan Chen, Zaimin Liu, Huilin Li, Xiaolei Wang, Xingang Xie,and Xuegong She*, Org. Lett. 2019, 21, 8718−8721. 

6. Bioinspired total synthesis of (−)-gymnothelignan L Peng Chen, Liang Huo, Huilin Li, Lin Liu, Ziyun Yuan, Hao Zhang, Shangbiao Feng, Xingang Xie, Xiaolei Wang  Xuegong She* Org. Chem. Front., 2018, 5, 1124.

7.“Total synthesis of conosilane A via a site-selective C–H functionalization strategy”. Ziyun Yuan, Xiaojun Hu, Hao Zhang, Lin Liu, Peng Chen, Min He, Xingang Xie, Xiaolei Wang and Xuegong She*, Chem. Commun., 2018, 54, 912—915.

8.“Palladium-Promoted Neutral 1,4-Brook Rearrangement/Intra- molecular Allylic Cyclization Cascade Reaction: A Strategy for the Construction of Vinyl Cyclobutanols”. Hao Zhang, Shiqiang Ma, Ziyun Yuan, Peng Chen, Xingang Xie, Xiaolei Wang, and Xuegong She*, Org. Lett. 2017, 19, 3478−3481.

9.“(3 + 2)-Annulation of p‑Quinamine and Aryne: A Strategy To Construct the Multisubstituted Hydrocarbazoles”. Dengyu Xu, Yulong Zhao, Dengpeng Song, Zhuliang Zhong, Shangbiao Feng, Xingang Xie, Xiaolei Wang, and Xuegong She*, Org. Lett. 2017, 19, 3600−3603.

10.  “Visible-light-mediated radical insertion/cyclization cascade reaction: synthesis of phenanthridines and isoquinolines from isocyanides”. Shangbiao Feng, Tao Li, Chenglong Du, Peng Chen, Dengpeng Song, Jinlai Li, Xingang Xie and Xuegong She *, Chem. Commun., 2017, 53, 4585—4588.

11. “Bioinspired Collective Syntheses of Iboga-Type Indole Alkaloids”. Gaoyuan Zhao, Xingang Xie, Haiyu Sun, Ziyun Yuan, Zhuliang Zhong, Shouchu Tang, and Xuegong She*, Org. Lett. 2016, 18, 2447−2450.

12. “Short and Scalable Total Synthesis of Myrioneuron Alkaloids (±)-α,β-Myrifabral A and B”. Dengpeng Song, Zhengshen Wang, Ruoming Mei, Weiwei Zhang, Donghui Ma, Dengyu Xu, Xingang Xie, and Xuegong She*, Org. Lett. 2016, 18, 669−671.

13. “Protecting-Group-Free Total Synthesis of (−)-Lycopodine via Phosphoric Acid Promoted Alkyne Aza-Prins Cyclization". Donghui Ma, Zhuliang Zhong, Zaimin Liu, Mingjie Zhang, Shiyan Xu, Dengyu Xu, Dengpeng Song, Xingang Xie, and Xuegong She*, Org. Lett. 2016, 18, 4328−4331.

14. “Gold-Catalyzed 1, 2-Acyloxy Migration/Intramolecular [3+2] 1, 3-Dipolar Cycloaddtion Cascade Reaction: An Efficient Strategy for Syntheses of Medium-Sized-Ring Ethers and Amines”. Changgui Zhao, Xingang Xie, Shuangshuang Duan, Huilin Li, Ran Fang, and Xuegong She*, Angew. Chem. Int. Ed. 2014, 53, 10789 –10793.

15. “N‑Heterocyclic Carbene-Catalyzed Formal [3+2] Annulation of Alkynyl Aldehydes with Nitrosobenzenes: A Highly Regioselective Umpolung Strategy”. Runfeng Han, Jing Qi, Jixiang Gu, Donghui Ma, Xingang Xie, and Xuegong She*, ACS Catal. 2013, 3, 2705−2709.

16. “Pt-Catalyzed Tandem 1, 2-Acyloxy Migration/Intramolecular [3 + 2] Cycloaddition of Enynyl Esters”. Huaiji Zheng, Jiyue Zheng, Binxun Yu, Qiang Chen, Xiaolei Wang, Yongping He, Zhen Yang, and Xuegong She* , J. Am. Chem. Soc. 2010, 132, 1788–1789.

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