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苏州纳米所王强斌研究员学术报告

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报 告 人:王强斌 研究员
报告题目:Advanced In Vivo Fluorescence Imaging: Seeing is Believing
报告时间:2018年11月19日(星期一)下午 15:00
报告地点:第二化学楼101学术报告厅
 
报告人简介
王强斌,博士、中科院“百人计划”研究员、博士生导师、国家杰出青年基金获得者。2002年于华东理工大学获博士学位,2004至2008年在美国亚利桑那州立大学从事博士后和助理研究教授工作,2008年7月年加入中科院苏州纳米所,任研究员、课题组长,主要从事新型近红外二区荧光活体影像技术及其转化医学研究,研究成果获2017年江苏省科学技术一等奖。获中科院“百人计划”结题优秀、国家自然科学基金委杰出青年基金、日本化学会“Distinguished Lectureship Award”、英国皇家化学会会士、科技部中青年科技创新领军人才等荣誉。目前,担任苏州纳米所所长助理、中科院纳米-生物界面重点实验室主任、Nano Research杂志编委等。
 
报告摘要
Fluorescent imaging in the second near-infrared window (NIR-II, 1.0~1.4 μm) is appealing in in vivo imaging due to minimal autofluorescence and negligible tissue scattering in this region, affording maximal penetration depth for deep tissue imaging with high feature fidelity. Herein, for the first time, we reported a new type of NIR-II QDs-Ag2S QDs and executed a series of in vivo imaging studies by using Ag2S QDs. The results show that, by using Ag2S QDs, the tissue penetration length can reach 1.5 cm, and the spatial and temporal resolution of the in vivo imaging can down to 25 ?m and 50 ms, respectively, which are improved several to dozens of times in comparison with those using conventional fluorescence nanoprobes in the visible and the first near-infrared window (650-900 nm), offering in situ, real-time visualization of the biological events in vivo. With the advanced NIR-II fluorescence of Ag2S QDs, high signal to noise ratio imaging of tumor growth and angiogenesis, imaging-guided targeting drug-delivery and therapeutics, imaging-guided precision surgery of glioma, and stem cell tracking and regeneration in vivo, etc., have been achieved.
 

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