•教育背景、工作经历
2009-至今 兰州大学功能有机分子化学国家重点实验室,副教授
2005-2009 兰州大学功能有机分子化学国家重点实验室,讲师
2016-2017 美国德州理工大学,访问学者
2009-2010 美国密苏里大学,访问学者
2002-2005 中国科学院兰州化学物理研究所,博士
1999-2002 兰州大学化学化工学院,硕士
1995-1999 兰州大学化学化工学院,学士
•研究兴趣
(1)天然化合物分子结构多样性的研究;
(2)中草药中具有生物活性分子的发现;
(3)天然化合物分子中酶抑制剂的发现及其作用机理的研究。
•代表成果
1. Structurally Diverse Diterpenoids from the Roots of Euphorbia Fischeriana Steud. Ya Li, Xingzhi Jiao, Tinghong Lv, Meili Yang, and Kun Gao*, Fitoterapia 2022, 162, 105296.
2. New Acylglycosides from the Roots of Rheum palmatum L. Wei-Jiao Feng, Hong-Ying Yang, Yi-Lin He, Ya Li*, and Kun Gao*, Phytochem. Lett. 2022, 49, 83.
3. Isolation, Identification, and Activity Evaluation of Diterpenoid Alkaloids from Aconitum Sinomontanum. Ya Li*, Jun Zeng, Yu-hua Tian, Yanan Hou, Honghong Da, Jianguo Fang, Kun Gao*, Phytochemistry 2021, 190, 112880.
4. Chemical Structures of Lignans and Neolignans Isolated from Lauraceae. Ya Li*, Shuhan Xie, Jinchuan Ying, Wenjun Wei, and Kun Gao*. Molecules 2018, 23, 3164.
5.Phytotoxic ent-Isopimarane-Type Diterpenoids from Euphorbia hylonoma. Wenjun Wei, Qiuyan Song, Zaiqin Zheng, Xiaojun Yao, Ya Li*, and Kun Gao*. J. Nat. Prod. 2018, 81, 2381-2391.
6. Antifungal Activities of Isoflavonoids from Uromyces striatus Infected Alfalfa. Ya Li, Guangda Li, Hitao Yu, Xingzhi Jiao, and Kun Gao*.Chem. Biodivers. 2018, 15, e1800407.
7. Diterpenoids from Salvia miltiorrhiza and their immune-modulating activity. Wenjun Wei, Panpan Zhou, Changjun Lin, Weifeng Wang, Ya Li*, and Kun Gao*. J. Agr. Food Chem. 2017, 65, 5985−5993.
8. Aphapolins A and B: Two Nemoralisin Diterpenoids Isolated from Aphanamixis polystachya (Wall.) Fuhu Fang, Wenjun Huang, Shuangyan Zhou, Zhengzhi Han, Manyu Li, Lifang Liu, Xiaozhen Wu, Xiaojun Yao, Ya Li*, and Chengshan Yuan*. Eur. J. Org. Chem. 2017, 4429-4433.
9. Spirochensilides A and B, two new rearranged triterpenoids from Abies chensiensis. Qianqian Zhao, Qiuyan Song, Kan Jiang, Guangda Li, Wenjun Wei, Ya Li*, and Kun Gao*. Org. Lett. 2015, 17, 2760-2763.
10. New lignans from the roots of Schisandra sphenanthera. Kan Jiang, Qiuyan Song, Shoujiao Peng, Qianqian Zhao, Guangda Li, Ya Li*, and Kun Gao*. Fitoterapia 2015, 103, 63-70.
11. Inactivation of Protein Tyrosine Phosphatases by Dietary Isothiocyanates. Sarah M.Lewis, Ya Li, Michael J. Catalano, Adrian R.Laciak, HarkewalSingh, Derrick R.Seiner, Thomas J.Reilly, John J.Tanner, and Kent S.Gates*. Bioorg. Med. Chem. Lett. 2015, 25, 4549–4552.
12. Thiophene acetylenes and furanosesquiterpenes from Xanthopappus subacaulis and their antibacterial activities. Li Zhang, Chaojun Chen, Jia Chen, Qianqian Zhao, Ya Li*, and Kun Gao*. Phytochemistry 2014, 106, 134-140.
13. An unusual indole alkaloid with anti-adenovirus and anti-HSV activities from Alstonia scholaris. Li Zhang, Chunjiang Zhang, Dongbo Zhang, Juan Wen, Xiaowei Zhao, Ya Li*, and Kun Gao*. Tetrahedron Lett. 2014, 55, 1815-1817.
14. Trinorsesquiterpenoids from Inula racemose. Yanyan Ma, Denggao Zhao, Ying Zhai, Ya Li*, and Kun Gao*. Phytochemistry Lett. 2013, 6, 645-648.
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