•教育背景、工作经历
2020-至今 兰州大学化学化工学院、功能有机分子化学国家重点实验室，教授
2012-2020 兰州大学化学化工学院、功能有机分子化学国家重点实验室，副教授
2009-2012 诺华生物医学研究中心（CNIBR） （导师: 江磊），博士后
2004-2009 中国科学院上海有机化学研究所 (导师: 伍贻康)，理学博士
2000-2004 四川大学，工学学士
·荣誉奖励
2020 德国“Thieme Chemistry Journals Award”
2019 入选甘肃省“飞天学者特聘计划”青年学者
2019 亚洲核心计划“ACP Lectureship Award”
•研究兴趣
天然产物全合成，有机合成方法学及药物化学
•代表成果
1. Diastereoselective Ring Expansion of Cyclic Ketones Enabled by Hat-Initiated Radical Cascade. Wenxue Wang, Shouyang Feng, Yansheng Wei, Hongyu Wang, and Yun Li*, Org. Lett. 2023, 25, 8022.
2. Synthetic studies on pseudolaric acid B: Enantioselective synthesis of C4,C10-di-epi-trans-fused [5-7]-bicyclic skeleton. Rui Guo, Hongbin Zhai*, and YunLi*. Chin. Chem. Lett. 2021, 32, 1400-1402.
3. Enantioselective Total Synthesis of (+)-Arboridinine. Zhang Zhen, Xie Sujun, Cheng Bin, Zhai Hongbin*, and Li Yun*. J. Am. Chem. Soc. 2019, 141, 7147-7154.
4. Facile Synthesis of Pyridines from Propargyl Amines: Concise Total Synthesis of Suaveoline Alkaloids. Zhao Zhiwen, Wei Hongbo, Xiao Ke, Cheng Bin, Zhai Hongbin, and Li Yun*. Angew. Chem. Int. Ed. 2019, 58, 1148-1152.
5. Stereoselective Synthesis of Spiro-2-oxabicyclo[2.2.2]octane Enabled by Ag(I)/ Brønsted Acid Relay Catalysis. Zhang Qingyu, Wang Jianping, Wei Yansheng, Zhai Hongbin, and Li Yun*. Org. Lett. 2019, 21, 1694-1698
6. Quick Access to Pyridines through 6π-3-Azatriene Electrocyclization: Concise Total Synthesis of Suaveoline Alkaloids. Wei Hongbo, and Li Yun*. Synlett 2019, 30, 1615-1620.
7. Relay Catalysis of Rh (II) and Cobaloxime: Stereoselective Synthesis of Spiroindanones from N-Sulfonyl-1,2,3-triazoles. Zhao Liu, Qiuchen Du, Hongbin Zhai, and Yun Li*. Org. Lett. 2018. 20, 7514-7517.
8. Organocatalytic Synthesis of 4-Aryl-1,2,3,4-tetrahydropyridines from Morita-Baylis-Hillman Carbonates through a One-Pot Three-Component Cyclization. Jian Wei, Yuntong Li, Cheng Tao, Huifei Wang, Bin Cheng, Hongbin Zhai*, and Yun Li*. J. Org. Chem. 2018, 83, 835-842.
9. The Expanding Utility of Rhodium-Iminocarbenes: Recent Advances in the Synthesis of Natural Products and Related Scaffolds. Yun Li*, Hongjian Yang, and Hongbin Zhai*. Chem.-Eur. J. 2018, 24, 12757-12766.
10. Bioinspired Total Synthesis of (±)-Chaetophenol C Enabled by a Pd-Catalyzed Cascade Cyclization. Yun Li*, Qingyu Zhang, Hongyu Wang, Bin Cheng, and Hongbin Zhai*. Org. Lett. 2017, 19, 4387-4390.
11. Rhodium-Catalyzed Denitrogenative [3+2] Cycloaddition: Access to Functionalized Hydroindolones and the Framework of Montanine-Type Amaryllidaceae Alkaloids. Hongjian Yang, Shengtai Hou, Cheng Tao, Zhao Liu, Chao Wang, Bin Cheng, Yun Li*, and Hongbin Zhai*. Chem.–Eur. J. 2017, 23, 12930-12936.
12. Cobaloxime-catalyzed hydration of terminal alkynes without acidic promoters. Shengtai Hou, Hongjian Yang, Bin Cheng, Hongbin Zhai*, and Yun Li*. Chem. Commun. 2017, 53, 6926-6929.
13.Rh-Catalyzed [3+2] Cycloaddition of 1-Sulfonyl-1,2,3-triazoles: Access to the Framework of Aspidosperma and Kopsia Indole Alkaloids. Yun Li*, Qingyu Zhang, Qiucheng Du, and Hongbin Zhai*. Org. Lett. 2016, 18, 4076-4079.
14. Synthesis of Polysubstituted Pyridines via a One-Pot Metal-Free Strategy. Hongbo Wei, Yun Li*, Ke Xiao, Bin Cheng, Huifei Wang, Lin Hu, and Hongbin Zhai*. Org. Lett. 2015, 17, 4076-4079.
15.Stereoselective Synthesis of (2Z)-2,4-Dienamides via NBS-Mediated Allyloxyl Addition-Claisen Rearrangement−Dehydrobromination Cascade Reaction of Ynsulfonamides. Runbo Ding, Yun Li*, Cheng Tao, Bin Cheng, and Hongbin Zhai*. Org. Lett. 2015, 17, 3994-3997.
Copyrights © All Rights Reserved 版权所有 兰州大学功能有机分子化学国家重点实验室 陇ICP备10000336号
