谢志翔 博士、教授、博士生导师 邮箱： xiezx@lzu.edu.cn

•教育背景、工作经历

2013-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室，教授

2012-2013           斯坦福大学（导师: Barry M. Trost）高级访问学者

2010-2012           兰州大学化学化工学院、功能有机分子化学国家重点实验室，教授

2004-2010           兰州大学化学化工学院、功能有机分子化学国家重点实验室，副教授

2002-2004           北京大学化学与分子工程学院 (导师: 杨震)，博士后

1999-2002           兰州大学化学化工学院 (导师: 李瀛)，理学博士

1996-1999           兰州大学化学系，理学硕士

1992-1996           广西大学化工系，工学学士

•研究兴趣

1. 具有抗艾滋病活性的天然产物不对称合成研究

2. 天然产物仿生合成及合成方法学研究 

3. 药物合成工艺开发与物质合成 

•代表成果

1. Highly Stereocontrolled Total Syntheses of Cedrane Sesquiterpenes via Cascade [5+2] Cycloaddition/ Etherification. Yuhan Zhang, Zhiyong Chi, Xiangxin Li, and Zhixiang Xie*, Chin. J. Chem. 2022, 40, 183-189.

2. Scalable Total Synthesis of (+)- and (−)-Codonopiloneolignanin A via Ti(IV)/NHC Cooperative Control Highly Enantioselective Dimerization of Multisubstituted Cinnamaldehyde. Xiangxin Li, Huaya Yong, Xiaohong Fan, Yajuan Zheng, Zhen Wang, Zhixiang Xie*, Org. Lett. 2021, 23, 6573-6577.

3. Total Synthesis of (±)-Spiroaxillarone A. Minjian Liao, Xiangxin Li, Yajuan Zheng, Zhixiang Xie*, J. Org. Chem. 2021, 86, 4835-4842.

4. Total Synthesis of Nominal ent-Chlorabietol B. Yulong Li, Zhezhe Xu, Zhipeng Xie, Xingchao Guan, and Zhixiang Xie*. J. Org. Chem. 2020, 85, 5724-5732.

5. Biomimetic Synthesis of Psiguajdianone Guided Discovery of the Meroterpenoids from Psidium guajava. Shuai Ning, Zhenling Liu, Zhichao Wang, Minjian Liao, and Zhixiang Xie*. Org. Lett. 2019, 21, 8700-8704.

6. Structural Elucidation and Total Synthesis of Three 9-Norlignans from Curculigo capitulate, Song Li, Jinhai Yu, Yaoyue Fan, Qunfang Liu, Zhanchao Li, Zhixiang Xie, Ying Li*, and Jianmin Yue*. J. Org. Chem. 2019, 84 , 5195-5202. 

7. Biomimetic Synthesis of Isorosmanol and Przewalskin A. Zhongle Li, Xun Zhang, Zhenjie Yang, Yuhan Zhang, and Zhixiang Xie* .J. Org. Chem. 2018, 83, 437-442.

8. Biomimetic Syntheses of C23 Terpenoids: Structural Revision of Salyunnanin A and Confirmation of Hassanane, Xun Zhang, Zhongle Li, Huaya Yong, and Zhixiang Xie*. Org. Chem. Front. 2018, 5, 3469-3475.

9. Biomimetic Syntheses of Callistrilones A–E via an Oxidative [3 + 2] Cycloaddition, Yonghong Guo, Yuhan Zhang, Mingxing Xiao, and Zhixiang Xie*. Org. Lett. 2018, 20, 2509-2512.

10. A highly efficient synthesis of the DEFG-ring system of rubriflordilactone B. Wang, Y.; Zhang, Y. H.; Li, Z. L.; Yang, Z. J.; Xie, Z. X.* Org. Chem. Fron. 2017, 4, 47-51.

11. Biomimetic Total Synthesis of Paeoveitol. Zhang, Y. H.; Guo, Y. H.; Li, Z. L.; Xie, Z. X.* Org. Lett. 2016, 18, 4578-4581.

12. Synthetic Study of Rubriflordilactone B: Highly Stereoselective Construction of the C-5-epi ABCDE Ring System. Wang, Y.; Li, Z. L.; Lv, L. B.; Xie, Z. X.* Org. Lett. 2016, 18, 792-795.

13. Cu/Mn Co-oxidized Cyclization for the Synthesis of Highly Substituted Pyrrole Derivatives from Amino Acid Esters: A Strategy for the Biomimetic Syntheses of Lycogarubin C and Chromopyrrolic Acid. Zhou, N. N.; Xie, T.; Liu, L.; Xie, Z. X.* J. Org. Chem. 2014, 79, 6061-6068.

14. Total Syntheses of (−)-Spirooliganones A and B. Wei, L.; Xiao, M. X.; Xie, Z. X.* Org. Lett. 2014, 16, 2784-2786.

15. Total Synthesis of (±)-Przewalskin B. Xiao, M. X.; Wei, L.; Li, L. Q.; Xie, Z. X.* J. Org. Chem. 2014, 79, 2746-2750.

16. Biomimetic Total Synthesis of (-)-Isatisine A . Wu, W.; Xiao, M. X.; Wang, J. B.; Li, Y.; Xie, Z. X.* Org. Lett. 2012, 14, 1624-1627.

17. Biomimetic Synthesis of Hyperolactones. Wu, Y. Y.; Du, C.; Hu, C. C.; Li, Y.; Xie, Z. X.* J. Org. Chem. 2011, 76, 4075-4081.

18. Construction of Two Vicinal Quaternary Carbons by Asymmetric Allylic Alkylation: Total Synthesis of Hyperolactone C and (-)-Biyouyanagin A . Du, C.; Li, L Q.; Li, Y.; Xie, Z. X.* Angew. Chem. Int. Ed. 2009, 48, 7853-7856.