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谢志翔

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谢志翔

博士、教授

邮箱: xiezx@lzu.edu.cn

•教育背景、工作经历

2013-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授

2012-2013           斯坦福大学(导师: Barry M. Trost)高级访问学者

2010-2012           兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授

2004-2010           兰州大学化学化工学院、功能有机分子化学国家重点实验室,副教授

2002-2004           北京大学化学与分子工程学院 (导师: 杨震),博士后

1999-2002           兰州大学化学化工学院 (导师: 李瀛),理学博士

1996-1999           兰州大学化学系,理学硕士

1992-1996           广西大学化工系,工学学士

•研究兴趣

1. 具有抗艾滋病活性的天然产物不对称合成研究

2. 天然产物仿生合成及合成方法学研究 

3. 药物合成工艺开发与物质合成 

•代表成果

 1. Biomimetic Synthesis of Psiguajdianone Guided Discovery of the Meroterpenoids from Psidium guajava,Shuai Ning, Zhenling Liu, Zhichao Wang, Minjian Liao, and Zhixiang Xie*, Org. Lett. 2019, 21, 8700–8704.

2. Structural Elucidation and Total Synthesis of Three 9-Norlignans from Curculigo capitulate, Song Li, Jin-Hai Yu, Yao-Yue Fan, Qun-Fang Liu, Zhan-Chao Li, Zhi-Xiang Xie, Ying Li*, and Jian-Min Yue*, J. Org. Chem., 2019, 84 (9), 5195–5202. 

3. Biomimetic Synthesis of Isorosmanol and Przewalskin A, Zhongle Li, Xun Zhang, Zhenjie Yang, Yuhan Zhang, and Zhixiang Xie* J. Org. Chem. 2018, 83(1), 437-442.

4. Biomimetic Syntheses of C23 Terpenoids: Structural Revision of Salyunnanin A and Confirmation of Hassanane, Xun Zhang, Zhongle Li, Huaya Yong, Zhixiang Xie*, Org. Chem. Front. 2018, 5, 3469 - 3475.

5. Biomimetic Syntheses of Callistrilones A–E via an Oxidative [3 + 2] Cycloaddition, Yonghong Guo, Yuhan Zhang, Mingxing Xiao, and Zhixiang Xie*. Org. Lett. 2018, 20, 2509–2512.

6. " A highly efficient synthesis of the DEFG-ring system of rubriflordilactone B". Wang, Y.; Zhang, Y. H.; Li, Z. L.; Yang, Z. J.; Xie, Z. X.* Org. Chem. Fron., 2017, 4, 47 – 51.

7. "Biomimetic Total Synthesis of Paeoveitol". Zhang, Y. H.; Guo, Y. H.; Li, Z. L.; Xie, Z. X.* Org. Lett. 2016, 18, 4578−4581.

8. " Synthetic Study of Rubriflordilactone B: Highly Stereoselective Construction of the C-5-epi ABCDE Ring System". Wang, Y.; Li, Z. L.; Lv, L. B.; Xie, Z. X.* Org. Lett. 2016, 18, 792-795.

9. " Cu/Mn Co-oxidized Cyclization for the Synthesis of Highly Substituted Pyrrole Derivatives from Amino Acid Esters: A Strategy for the Biomimetic Syntheses of Lycogarubin C and Chromopyrrolic Acid". Zhou, N. N.; Xie, T.; Liu, L.; Xie, Z. X.* J. Org. Chem. 2014, 79, 6061–6068.

10. " Total Syntheses of (−)-Spirooliganones A and B". Wei, L.; Xiao, M. X.; Xie, Z. X.* Org. Lett. 2014, 16, 2784–2786.

11. " Total Synthesis of (±)-Przewalskin B". Xiao, M. X.; Wei, L.; Li, L. Q.; Xie, Z. X.* J. Org. Chem. 2014, 79, 2746–2750.

12. " Biomimetic Total Synthesis of (-)-Isatisine A ". Wu, W.; Xiao, M. X.; Wang, J. B.; Li, Y.; Xie, Z. X.* Org. Lett. 2012, 14, 1624-1627.

13." Biomimetic Synthesis of Hyperolactones". Wu, Y. Y.; Du, C.; Hu, C. C.; Li, Y.; Xie, Z. X.* J. Org. Chem. 2011, 76, 4075–4081.

14." Construction of Two Vicinal Quaternary Carbons by Asymmetric Allylic Alkylation: Total Synthesis of Hyperolactone C and (-)-Biyouyanagin A ". Du, C.; Li, L Q.; Li, Y.; Xie, Z. X.* Angew. Chem. Int. Ed. 2009, 48, 7853-7856.

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