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彭 羽

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彭羽

博士、教授、博士生导师

邮箱: pengyu@lzu.edu.cn

•教育背景、工作经历

2014-至今            兰州大学化学化工学院、功能有机分子化学国家重点实验室,教授

2009-2014           兰州大学化学化工学院、功能有机分子化学国家重点实验室,副教授

2008-2009           加州大学圣芭芭拉分校 (导师: Liming Zhang教授),博士后

2005-2009           兰州大学化学化工学院、功能有机分子化学国家重点实验室,讲师

2000-2005           兰州大学 (导师: 李卫东教授),理学博士

1996-2000           兰州大学,理学学士

研究兴趣

天然产物全合成,镍催化的还原偶联反应,小分子荧光探针的多样性合成

代表成果 

1. Base-Promoted Addition of DMA with 1,1-Diarylethylenes: Application to a Total Synthesis of (-)-Sacidumlignan B. Zhenbiao Luo, Yawen Wang, and Yu Peng*.  Org. Biomol. Chem. 2020, 18, 2054-2057.

2. Divergent Total Syntheses of C3a-C7′ Linked Diketopiperazine Alkaloids (+)-Asperazine and (+)-Pestalazine A Enabled by a Ni-Catalyzed Reductive Coupling of Tertiary Alkyl Chloride. Long Luo, Xiaoyong Zhai, Yawen Wang, Yu Peng*, and Hegui Gong*. Chem.-Eur. J. 2019, 25, 989-992. 

3. A Water-Soluble Dual-Site Fluorescent Probe for the Rapid Detection of Cysteine with High Sensitivity and Specificity. Baojun Wang, Ruijuan Liu, Jianguo Fang, Yawen Wang*, and Yu Peng*, Chem. Commun. 2019, 55, 11762-11765.  

4. Divergent Asymmetric Syntheses of Podophyllotoxin and Related Family Members via Stereoselective Reductive Ni-Catalysis. Jian Xiao,  Xiaowei Cong, Guizhen Yang, Yawen Wang, and Yu Peng*. Org. Lett. 2018, 20, 1651-1654. (Highlighted by CBG). 

5. Stereoselective Synthesis of a Podophyllum Lignan Core by Intramolecular Reductive Ni-Catalysis. Jian Xiao, Xiaowei Cong, Guizhen Yang, Yawen Wang, and Yu Peng*.  Chem. Commun. 2018, 54, 2040-2043. (Highlighted by X-MOL) 

6. Sensitive Fluorescence On-off Probes for the Fast Detection of a Chemical Warfare Agent Mimic. Muhammad Shar Jhahan Khan, Yawen Wang*, Mathias O. Senge, and Yu Peng*. J. Hazard. Mater. 2018, 342, 10-19.

7. Two Fluorescein-based Chemosensors for the Fast Detection of 2, 4, 6-Trinitrophenol (TNP) in Water. Fu Zhenhai, Wang Yawen*, and Peng Yu*. Chem. Commun. 2017, 53, 10524-10527. (Chemosensors and Molecular Logic themed issue)

8. A Series of Fluorescent and Colorimetric Chemodosimeters for Selective Recognition of Cyanide Based on the FRET Mechanism. Hua Yingxi, Shao Yongliang, Wang Yawen*, and Peng Yu*. J. Org. Chem. 2017, 82, 6259-6267.

9. Fluorescein-based Chromogenic and Ratiometric Fluorescence Probe for Highly Selective Detection of Cysteine and Its Application in Bioimaging. Fu Zhenhai, Han Xiao, Shao Yongliang, Fang Jianguo, Zhang Zhihong, Wang Yawen*, and Peng Yu*. Anal. Chem. 2017, 89, 1937-1944. (Highlighted by X-MOL)

10. Stereospecific Synthesis of Tetrahydronaphtho[2,3-b]furans Enabled by a Nickel-Promoted Tandem Reductive Cyclization. Peng Yu*, Xiao Jian, Xu Xiaobo, Duan Shuming, Ren Li, Shao Yongliang, and Wang Yawen. Org. Lett. 2016, 18, 5170-5173. (Highlighted by Prof. Paul Knochel in Synfacts 2016, 12, 1296. and X-MOL)

11. A Fluorescent Probe for Relay Recognition of Homocysteine and Group IIIA Ions Including Ga(III). Wang Yawen, Liu Shunbang, Ling Weijian, and Peng Yu*. Chem. Commun. 2016, 52, 827-830.

12. A Terbium(III)-Complex-Based On-Off Fluorescent Chemosensor for Phosphate Anions in Aqueous Solution and Its Application in Molecular Logic Gates. Wang Yawen, Liu Shunbang, Yang Yanling, Wang Pengzhi, Zhang Aijiang, and Peng Yu*. ACS Appl. Mater. Inter. 20157, 4415-4422.

13. Nickel-Mediated Stereocontrolled Synthesis of Spiroketals via Tandem Cyclization-Coupling of β-Bromo Ketals and Aryl Iodides. Peng Yu*, Xu Xiaobo, Xiao Jian, and Wang Yawen. Chem. Commun. 2014, 50, 472-474. 

14. Ni-Catalyzed Reductive Homocoupling of Unactivated Alkyl Bromides at Room Temperature and Its Synthetic Application. Peng Yu*, Luo Long, Yan Changsong, Zhang Jianjian, and Wang Yawen. J. Org. Chem. 2013, 78, 10960-10967.

15. Nickel-Mediated Inter- and Intramolecular C-S Coupling of Thiols and Thioacetates with Aryl Iodides at Room Temperature. Xu Xiaobo, Liu Jian, Zhang Jianjian, Wang Yawen, and Peng Yu*. Org. Lett. 2013, 15, 550-553.

16. Nickel-Mediated Inter- and Intramolecular Reductive Cross-Coupling of Unactivated Alkyl Bromides and Aryl Iodides at Room Temperature. Yan Changsong, Peng Yu*, Xu Xiaobo,and  Wang Yawen. Chem.-Eur. J. 2012, 18, 6039-6048.

17. A Selective and Ratiometric Bifunctional Fluorescent Probe for Al3+ Ion and Proton. Sun Xin, Wang Yawen, and Peng Yu*. Org. Lett. 2012, 14, 3420-3423.

18. A Selective, Sensitive, Colorimetric, and Fluorescence Probe for Relay Recognition of Fluoride and Cu(II) Ions with “Off-On-Off” Switching in Ethanol-Water Solution. Peng Yu*, Dong Yuman, Dong Ming, and Wang Yawen*. J. Org. Chem. 2012, 77, 9072-9080.

19. A Selective, Colorimetric, and Fluorescent Chemodosimeter for Relay Recognition of Fluoride and Cyanide Anions Based on 1, 1'-Binaphthyl Scaffold. Dong Ming, Peng Yu, Dong Yuman, Tang Ning, and Wang Yawen*. Org. Lett. 2012, 14, 130-133.

20. A Selective, Sensitive, and Chromogenic Chemodosimeter for Cyanide Based on the 1, 1'-Binaphthyl Scaffold. Dong, Yuman; Peng Yu*, Dong Ming, and Wang Yawen*. J. Org. Chem. 2011, 76, 6962-6966.

21. A Colorimetric and Fluorescent Chemosensor for the Detection of an Explosive-2, 4, 6-Trinitrophenol (TNP). Peng Yu*, Zhang Aijiang, Dong Ming, and Wang Yawen*. Chem. Commun. 2011, 47, 4505-4507. (Top Ten Most Accessed Articles in March, 2011)

22. Highly Selective Ratiometric Fluorescent Sensing for Hg2+ and Au3+, Respectively, in Aqueous Media. Dong Ming, Wang Yawen*, and Peng Yu*. Org. Lett. 2010, 12, 5310-5313.

23. A Unique Water-Tuning Dual-Channel Fluorescence-Enhanced Sensor for Aluminum Ions Based on a Hybrid Ligand from a 1, 1'-Binaphthyl Scaffold and an Amino Acid. Ma Tianhua, Dong Ming, Dong Yuman, Wang Yawen*, and Peng Yu*. Chem.-Eur. J. 2010, 16, 10313-10318.

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