Qiang Liu  Ph D., Professor  E-mail:  liuqiang@lzu.edu.cn Mailing Address:  College of Chemistry and Chemical Engineering,  Lanzhou University, No.222 Tianshui South Road, Lanzhou, China

•Education and Experiences

2015-Present      Professor, Lanzhou University, China

2009-2015          Associate Professor, Lanzhou University, China

2009-2011          Postdoctoral Researcher, The Technical Institute of Physics and Chemistry of 

                            The Chinese Academy of Sciences, China 

                                  (Advisor:  Academician Li-Zhu Wu and Prof. Chen-Ho Tung)

2006-2009          Assistant Professor, Lanzhou University, China

2001-2006          Ph.D. in Organic Chemistry, Lanzhou University, China  

                            (Advisor: Prof. Zhong-Li Liu)

1997-2001          B.Sc., Lanzhou University, China

·Research Topics

1.Organic Photochemistry:  A main research focus in our laboratory is on sustainable substainable organic transformations driven by visible light. We are specifically focused on visible-light-driven aerobic oxidations and photochemical strategies which contribute to valuable molecules in a milder and safer manner.

2.Free Radical Chemistry: New catalytic processes and methods for highly cost- and atom-efficient radical reactions.

•Publications

1. Photoacid-Enabled Synthesis of Indanes via Formal [3 + 2] Cycloaddition of Benzyl Alcohols with Olefins. Biao Yang, Kui Dong, Xiang-Sheng Li, Li-Zhu Wu, and Qiang Liu*. Org. Lett. 2022, 24, 2040.

2. Highly Efficient Visible-Light-Driven [2+2] Cycloaddition of Maleimides to Alkenes and Alkynes for the Synthesis of 3-Aza­bicyclo[3.2.0]heptane-Fused Scaffolds. Jian He, and Qiang Liu∗. Synthesis 2022, 54, 925.

3. Metallaphotoredox Dearomatization of Indoles by a Benzamide-Empowered [4+2] Annulation: Facile Access to Indolo[2, 3-c]isoquinolin-5-ones.Yong-Liang Ban, Long You, Tao Wang, Li-Zhu Wu, and Qiang Liu*. ACS Catal. 2021, 11, 5054-5060.

4. Highly Efficient Iridium-Based Photosensitizers for Thia-Paternò-Büchi Reaction and Aza-Photocyclization. Jian He, Zhiqin Bai, Panfeng Yuan, Lizhu Wu, and Qiang Liu*. ACS Catal. 2021, 11, 446-455.

5. Bioinspired Selective Synthesis of Heterodimer 8-5’or 8-O-4’ Neolignan Analogs. Kui Dong, Chuang-Yuan Zhao, Xiao-Ju Wang, Li-Zhu Wu, and Qiang Liu*. Org. Lett. 2021, 23, 2816-2820.

6. Meyer-Schuster-Type Rearrangement of Propargylic Alcohols into α-Selenoenals and -enones with Diselenides. Yong-Liang Ban, Long You, Kai-Wen Feng, Fei-Cen Ma, Xiao-Ling Jin, and Qiang Liu*. J. Org. Chem. 2021, 86, 5274.

7. Controllable Z/E-Selective Synthesis of α-Amino α-Ketoximes from N-Nitrososulfonamides and Aryl Alkenes Under Neutral Conditions. Pan-Feng Yuan, Tao Huang, Jian He, Xie-Tian Huang, Xiao-Ling Jin, Chun lin Sun, Li-Zhu Wu, and Qiang Liu*. Org. Chem. Front. 2021, 8, 5785-5792.

8. Enantioselective Alkylation of Azoles by Merging Visible Light and Copper Catalysis. hengqiang Li, and Qiang Liu*. Chinese J. Org. Chem. 2021, 41, 863-864.

9. Preparation of Oxazole Acetals from N-Propargylamides Enabled by Visible-Light-Promoted Selenium-π-Acid Catalysis. Xue Yang Wang, Qing Bao Zhang, Xiao Ling Jin, Li Zhu Wu, and Qiang Liu*. ChemPhotoChem 2021, 5, 240-244.

10. Controllable synthesis of 2- and 3-arylbenzomorpholines from 2-aminophenols and 4-vinylphenols. Kui Dong, Xiaoling Jin, Shihao Chen, Lizhu Wu, and Qiang Liu*. Chem. Commun. 2020, 56, 7941-7944.

11. 放氢交叉偶联反应. 董奎，刘强*, 吴骊珠*. 化学学报，2020, 78, 299-310.

12. Synthesis of 4‑Oxoisoxazoline N-Oxides via Pd-Catalyzed Cyclization of Propargylic Alcohols with tert-Butyl Nitrite. Kaiwen Feng, Yongliang Ban, Panfeng Yuan, Wenlong Lei, Qiang Liu*, and Ran Fang*.Org. Lett. 2019, 21, 3131-3135.

13. Preparation of Heterocycles via Visible-Light-Driven Aerobic Selenation of Olefins with Diselenides. Qingbao Zhang, Panfeng Yuan, Lianglin Kai, Kai Liu, Yongliang Ban, Xueyang Wang, Lizhu Wu, and Qiang Liu*. Org. Lett. 2019，21, 885-889.

14. Thiocyanate Radical Mediated Dehydration of Aldoximes with Bisible Light and Air. Yongliang Ban, Jianling Dai, Xiaoling Jin, Qingbao Zhang,  Qiang Liu*. Chem. Commun. 2019, 55, 9701-9704.

15. Eosin Y- and Copper-Catalyzed Dark Reaction To Construct Ene-γ-Lactams. Wenlong Lei, Kaiwen Feng, Tao Wang, Lizhu Wu, and Qiang Liu*. Org. Lett. 2018, 20, 7220-7224.

16. Visible-light-enabled aerobic synthesis of benzoin bis-ether from alkynes and alcohols. Wenlong Lei, Biao Yang, Qingbao Zhang, Panfeng Yuan, Lizhu Wu, and Qiang Liu*. Green Chem. 2018, 20, 5464-5468.

17. Visible-light-promoted aerobic metal-free aminothiocyanation of activated ketones. Panfeng Yuan, Qingbao Zhang, Xiaoling Jin, Wenlong Lei, Lizhu Wu, and Qiang Liu*.Green Chem. 2018, 20, 5479-5483.

18. Visible-Light-Mediated Aerobic Selenation of (Hetero)Arenes with Diselenides. Qingbao Zhang, Yongliang Ban, Panfeng Yuan, Shoujiao Peng, Jianguo Fang, Lizhu Wu, and  Qiang Liu*.  Green Chem. 2017, 19, 5559-5563.

19. Visible-Light-Driven Synthesis of 4-Alkyl/Aryl-2-Aminothiazoles Promoted by In Situ Generated Copper Photocatalyst. Wenlong Lei, Tao Wang, Kaiwen Feng, Li-Zhu Wu, and Qiang Liu*. ACS Catal. 2017, 7, 7941-7945.

20. Recent advances in visible-light-driven organic reactions. Qiang Liu,  and Lizhu Wu*. Natl. Sci. Rev. 2017, 4, 359-380. 

21. Visible-Light-Driven Aromatization Hydrogen Evolution by Organic Dye and Ni Complex. Wang Xiaoju, Dong Kui, and Liu Qiang*. Acta Chimi. Sinica.  2017, 75 , 119 -122.

22. Preparation of α-Acyloxy Ketones via Visible-Light-Driven Aerobic Oxo-Acyloxylation of Olefins with Carboxylic Acids. Qingbao Zhang, Yongliang Ban, Dagang Zhou, Panan Zhou, Lizhu Wu, and Qiang Liu*. Org. Lett. 2016, 18, 5256-5259.

23. Domino Radical Addition/Oxidation Sequence with Photocatalysis: One-Pot Synthesis of Polysubstituted Furans from α-Chloro-Alkyl Ketones and Styrenes. Shuang Wang, Wenliang Jia, Lin Wang, Qiang Liu*, and Lizhu Wu*.Chem.-Eur. J. 2016, 22, 13794-13798.

24. Homocoupling of 3 Halooxindole via Visible-Light Photocatalysis: A Mild Access to 3, 3′-Bioxindoles. Wenliang Jia, Jian He, Jiajing Yang, Xuewang Gao, Qiang Liu*, and Lizhu Wu*. J. Org. Chem. 2016, 81, 7172-7181.

25. Autoxidation/Aldol Tandem Reaction of 2-Oxindoles with Ketones: A Green Approach for the Synthesis of 3-Hydroxy-2-Oxindoles. Qingbao Zhang, Wenliang Jia, Yongliang Ban, Yong Zheng, Qiang Liu*, and Lizhu Wu. Chem.-Eur. J. 2016, 22, 2595-2598.

26. Visible-light photoredox intramolecular difluoroacetamidation: facile synthesis of 3, 3-difluoro-2-oxindoles from bromodifluoroacetamides. Xiaojing Wei, Lin Wang, Shaofu Du, Lizhu Wu, and Qiang Liu*.Org. Biomol. Chem. 2016, 14, 2195-2199.

27. Combining visible light catalysis and transfer hydrogenation for in situ efficient and selective semihydrogenation of alkynes under ambient conditions. Jianji Zhong, Qiang Liu, Chengjuan Wu, Qingyuan Meng, Xuewang Gao, Zhijun Li, Bin Chen,   Chenho Tung, and Lizhu Wu*.Chem. Commun. 2016, 52, 1800-1803. 

28. Preparation of 6-Difluoromethylphosphonated Phenanthridines by Visible-Light-Driven Radical Cyclization of 2-Isocyanobiphenyls. Shuang Wang, Wenliang Jia, Lin Wang, and Qiang Liu*. Eur. J. Org. Chem. 2015, 6817-6821.

29. Visible-Light-Driven Intermolecular [2+2] Cycloadditions between Coumarin-3-Carboxylates and Acrylamide Analogs. Qiang Liu*, Fuping Zhu, Xiaoling Jin, Xiaoju Wang, Han Chen, and Lizhu Wu. Chem.-Eur. J. 2015, 21, 10326-10329. 

30. Direct C-H Difluoromethylenephosphonation of Arenes and Heteroarenes with Bromodifluoromethylphosphonate via Visible-Light Photocatalysis. Lin Wang, Xiaojing Wei, Wenlong Lei, Han Chen, Lizhu Wu, and Qiang Liu*. Chem. Commun. 2014, 50, 15916-15919.

31. Visible-Light-Driven Difluoroacetamidation of Unactive Arenes and Heteroarenes by Direct C−H Functionalization at Room Temperature. Lin Wang, Xiaojing Wei, Wenliang Jia, Jianji Zhong, Lizhu Wu, and Qiang Liu*.Org. Lett. 2014, 16, 5842-5845.

32. Metal-Free-Mediated Oxidation Aromatization of 1,4-Dihydropyridines to Pyridines Using Visible Light and Air. Xiaojing Wei, Lin Wang, Wenliang Jia, Shaofu Du, Lizhu Wu, and Qiang Liu*. Chinese J. Chem. 2014, 32, 1245-1250.

33. Synthesis of 2-substituted pyrimidines and benzoxazoles via a visible-light-driven organocatalytic aerobic oxidation: enhancement of the reaction rate and selectivity by a base. Lin Wang, Zhigang Ma, Xiaojing Wei, Qingyuan Meng, Dengtao Yang, Shaofu Du, Zifei Chen,  Lizhu Wu*, and Qiang Liu*. Green Chem. 2014, 16, 3752-3757.

34. Aerobic oxidative coupling of resveratrol and its analogues by visible light using mpg-C3N4 as a bio-inspired catalyst. Tao Song, Bo Zhou, Guangwei Peng, Qingbao Zhang, Lizhu Wu, Qiang Liu*, and Yong Wang. Chem.-Eur. J. 2014, 20, 678–682.

35. A Cascade Cross-Coupling Hydrogen Evolution Reaction by Visible Light Catalysis. Qingyuan Meng, Jianji Zhong, Qiang Liu, Xuewang Gao, Huihui Zhang, Tao Lei, Zhijun Li, Ke Feng, Bin Chen, Chen-Ho Tung, and Lizhu Wu*. J. Am. Chem. Soc. 2013, 135, 19052-19055.

36. Chitosan confinement enhances hydrogen photogeneration from a mimic of the diiron subsite of [FeFe]-hydrogenase. JingXin Jian, Qiang Liu, ZhiJun Li, Feng Wang, XuBing Li, ChengBo Li, Bin Liu, QingYuan Meng, Bin Chen, Ke Feng, Chen-Ho Tung, and Lizhu Wu*. Nat. Commun. 2013, 4, 2695.

37. A Novel Intermolecular Synthesis of γ-Lactones via Visible-Light Photoredox Catalysis. Xiaojing Wei, Dengtao Yang, Lin Wang, Tao Song, Lizhu Wu*, and Qiang Liu*. Org. Lett. 2013, 15 , 6054-6057.

38. Metal-Free Desulfonylation Reaction via Visible-Light Photoredox Catalysis. Dengtao Yang, Qingyuan Meng, Jianji Zhong, Ming Xiang, Qiang Liu, and Lizhu Wu*. Eur. J. Org. Chem. 2013, 33, 7528-7532.

39. Reactivity and Mechanistic Insight into Visible-Light-Induced Aerobic Cross-Dehydrogenative Coupling Reaction by Organophotocatalysts. Qiang Liu, Yanan Li, Huihui Zhang, Bin Chen, Chen‐Ho Tung, and Lizhu Wu*. Chem.-Eur. J. 2012, 18, 620-627.

40. Photochemical Preparation of Pyrimidin-2(1H)-ones by Rhenium(I) Complexes with Visible Light. Qiang Liu, Yanan Li, Huihui Zhang, Bin Chen, Chen-Ho Tung, and Lizhu Wu*. J. Org. Chem. 2011, 76, 1444-1447.

41. Selective Reduction of Nitroarenes by a Hantzsch 1, 4-Dihydropyridine: A Facile and Efficient Approach to Substituted Quinolines. Ruiguang Xing, Yanan Li, Qiang Liu*, Yifeng Han, Xia Wei, Jing Li, and Bo Zhou. Synthesis 2011, 2066-2072.

42. Facile and Efficient Synthesis of Benzoxazoles and Benzimidazoles: The Application of Hantzsch ester 1, 4-dihydropyridines in Reductive Cyclization Reactions. Ruiguang Xing, Yanan Li, Qiang Liu, Qingyuan Meng, Jing Li, Xiaoxia Shen, Zhengang Liu,  Bo Zhou, Xiaojun Yao, and Zhongli Liu. Eur. J. Org. Chem. 2010, 6627-6632. 

43. Highly Selective Semihydrogenation of Phenylalkynes to (Z)-Styrenes Using Hantzsch Ester 1, 4-Dihydropyridine Catalyzed by Pd/C. Yankai Zhao, Qiang Liu*, Jing Li, Zhongquan Liu, and Bo Zhou.Synlett 2010, 1870–1872.

44. First Use of HEH in Oxazine Synthesis: Hydroxy-Substituted 2H-1, 4-Benzoxazine Derivatives. Qingyuan Meng, Qiang Liu*, Jing Li, Ruiguang Xing, Xiaoxia Shen, Bo Zhou B. Synlett 2009, 3283-3286.

45. Hydrogenation of Olefins Using Hantzsch Ester Catalyzed by Palladium on Carbon. Qiang Liu*, Jing Li, Xiaoxia Shen, Ruiguang Xing, Jie Yang, Zhengang Liu, and Bo Zhou.Tetrahedron Lett. 2009, 50, 1026-1028.

46. Reduction of N-(alkoxy(aryl)methyl)benzamide Compounds by a Hantzsch Ester 1, 4-Dihydropyridine Using Pd/C as a Catalyst. Xiaoxia Shen, Qiang Liu, Ruiguang Xing, and Bo Zhou. Catal. Lett. 2008, 126, 361-366.