Yueting Wu

Ph.D., Associate Professor

E-Mail：

wuyt@lzu.edu.cn

Mailing Address：

222 South Tianshui Road, Lanzhou, Gansu, 730000, P. R. China

•Education and Experience

2016-Present          College of Chemistry and Chemical Engineering, Lanzhou University, 

                              State Key Laboratory of Applied Organic Chemistry, associate professor 

2015-2016              Center For Immunotherapy (CFI), Roswell Park Cancer Institute (RPCI), 

                              Buffalo, NY, USA, postdoctoral researcher. 

2009-2015              Department of Chemical Engineering, Department of Microbiology, 

                              Immunology, & Cell Biology, West Virginia University, Morgantown, 

                              WV, USA, Ph.D. graduate student.

2000-2006              College of Materials Science and Chemical Engineering, Zhejiang University, 

                              Hangzhou, China. B.S. and M.S. graduate student, majoring in Biochemical 

                              Engineering.

•Research Topics

Cancer immunotherapy and cancer immunology, cell-to-cell communication between cancer and immune cells. Nanosized biological particles (exosomes) isolated from cancer cells and/or immune cells. A variety of anti-cancer immunoregulating targets and their therapeutic effects, e.g. CTLA-4, PD1/PD-L1, LAG3. 

•Publications

1. Melanoma exosomes deliver a complex biological payload that upregulates PTPN11 to suppress T lymphocyte function. Yueting Wu, Wentao Deng, Emily Chambers McGinley, and David J. Klinke II*. Pigm.Cell Melanoma R. 2017, 30, 203-218. 

2. Exosomes: improved methods to characterize their morphology, RNA content, and surface protein biomarkers. Yueting Wu, Wentao Deng, and David J. Klinke II*..Analyst 2015, 140, 6631-6642.

3. Interlocked positive and negative feedback network motifs regulate beta-catenin activity in the adherens junction pathway. David J. Klinke*, Nicholas Horvath, Vanessa Cuppett, Yueting Wu, Wentao Deng, and Rania Kanj. Mol. Biol.Cell  2015, 26, 3893-4181. 

4. Inferring alterations in cell-to-cell communication in HER2+ breast cancer using secretome profiling of three cell models. David J. Klinke*, Nicholas Horvath, Vanessa Cuppett, Yueting Wu, Wentao Deng, and Rania Kanj. Biotechnol. Bioeng. 2014, 111, 1853-1863.

5. Selective filling of nanowells in nanowell arrays fabricated using polystyrene nanosphere lithography with cytochrome P450 enzymes. Lance A Wollenberg, John E Jett, Yueting Wu, Darcy R Flora, Nianqiang Wu, Timothy S Tracy, and Peter M Gannett. Nanotechnology 2012, 23, 385101.

6. Azathioprine hepatotoxicity and the protective effect of liquorice and glycyrrhizic acid. Yueting Wu, Chong Shen, Jian Yin, Jinpeng Yu, and Qin Meng*.Phytother Res. 2006, 20, 640-645.

7. Biodegradation of crude oil by Pseudomonas aeruginosa in the presence of rhamnolipids. Yueting Wu, Chong Shen, Jian Yin, Jinpeng Yu and Qin Meng*. 2005, 6, 725-730. (Indexed by EI, 2005).